Author

R. L. Finley

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Cancer Biology· 1

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:variant effect prediction· 1 Organism:yeast· 1

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C. E. McCarthy-Leo· 1 shared F. Luca· 1 shared G. S. Brush· 1 shared M. A. Tainsky· 1 shared R. Pique-Regi· 1 shared

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2023-2023 · peak 1/yr

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1 shared paperCancer Biology

C. E. McCarthy-Leo

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintDec 22, 2023

Comprehensive analysis of the functional impact of single nucleotide variants of human CHEK2

C. E. McCarthy-Leo, G. S. Brush, R. Pique-Regi…·R. L. Finley

The paper functionally tests most CHEK2 SNVs using a yeast complementation assay, finding 770 damaging and 2,417 tolerated variants, aiding in pathogenicity prediction.

DOI 10.1101/2023.12.22.573093

yeastDNA methylation

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