The appearance of sugI mixed loci in three individuals during treatment for MDR-TB, supports the involvement of sugI in Mycobacterium tuberculosis d-cycloserine resistance in vivo.
R. M. Anthony, M. Molemans, O. Akkwerman…·V. Crudu
This study identifies mixed SNPs in the sugI gene from M. tuberculosis isolates during MDR-TB treatment, suggesting a potential role of sugI in d-cycloserine resistance.