Cancer BiologybioRxiv
Suppression of endothelial miR-22-3p mediates non-small cell lung cancer cell-induced angiogenesis
Y. Gu, G. Pais, V. Becker…·M. W. Laschke
The paper shows that reduced endothelial miR-22-3p in NSCLC tissues promotes angiogenesis by inhibiting SIRT1 and FGFR1, leading to AKT/mTOR inactivation and tumor growth.
DOI 10.1016/j.omtn.2021.10.003