Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
M. E. Watts, R. M. Giadone, A. Ordureau…·L. L. Rubin
The paper uses ER stressors in ALS patient-derived motor neurons to identify druggable targets that protect against degeneration.
S. Ghosh, C. Villacorta-Martin, J. Lindstrom-Vautrin…·G. J. Murphy
The paper exposes cells to destabilized TTR variants and analyzes transcriptional and epigenetic responses to identify cell- and protein-specific signatures of amyloidogenic stress.
R. M. Giadone, D. C. Liberti, T. M. Matte…·G. J. Murphy
This study uses iPSC-derived hepatic cells to show that liver proteostasis factors and UPR signaling correlate with TTR amyloid production and can reduce amyloid secretion through ER stress-independent activation.