Author

R. Middlewick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

A. L. Tatler· 2 shared S. R. Johnson· 2 shared A. Bullock· 1 shared A. E. John· 1 shared A. Habgood· 1 shared A. John· 1 shared A. T. Goodwin· 1 shared B. S. Brook· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPhysiology

A. L. Tatler

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2 papers

Recent·Most cited

Differential remodelling in small and large murine airways revealed by novel whole lung airway analysis.

A. L. Tatler, C. J. Philp, M. R. Hill, S. Cox, A. Bullock, A. Habgood, A. John, R. Middlewick, K. E. Stephenson, A. T. Goodwin, C. K. Billington, R. D. O'Dea, B. S. Brook, S. R. Johnson

The paper uses a new method to analyze whole lung airway sections in mice, revealing differential remodelling in small and large airways after allergen challenge.

bioRxiv · Jan 15, 2022Physiology

Lysyl oxidase-like 2 (LOXL2) is Increased in Asthma and Contributes to Asthmatic Airway Remodelling

J. Ramis, R. Middlewick, F. Pappalardo, J. T. Cairns, I. D. Stewart, A. E. John, S.-u. Naveed, R. Krishnan, S. Miller, D. E. Shaw, C. E. Brightling, L. Buttery, F. R. Rose, G. Jenkins, S. R. Johnson, A. L. Tatler

This study shows LOXL2 is increased in asthma and contributes to airway remodelling by enhancing TGFβ activation and ECM stiffness.

bioRxiv · Nov 16, 2020 · PreprintCell Biology