Author

J. T. Cairns

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. L. Tatler· 2 shared I. D. Stewart· 2 shared A. E. John· 1 shared A. Habgood· 1 shared A. Nordheim· 1 shared B. C. Blaxall· 1 shared C. E. Brightling· 1 shared C. Wilkinson· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

A. L. Tatler

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintNov 16, 2020

Lysyl oxidase-like 2 (LOXL2) is Increased in Asthma and Contributes to Asthmatic Airway Remodelling

J. Ramis, R. Middlewick, F. Pappalardo…·A. L. Tatler

This study shows LOXL2 is increased in asthma and contributes to airway remodelling by enhancing TGFβ activation and ECM stiffness.

DOI 10.1101/2020.11.16.384792

𝕏 PostBluesky

PathologybioRxivSep 5, 2019

Loss of ELK1 has differential effects on age-dependent organ fibrosis and integrin expression

J. T. Cairns, A. Habgood, R. Edwards-Pritchard…·A. L. Tatler

This study shows that loss of ELK1 leads to age-related fibrosis in the lung and liver but not heart or kidneys, and links reduced ELK1 to cigarette smoke exposure.

DOI 10.1016/j.biocel.2019.105668

mouseexperimental assay

𝕏 PostBluesky