A map of the rubisco biochemical landscape
N. Prywes, N. R. Phillips, L. M. Oltrogge, S. Lindner, Y.-C. Tsai, B. de Pins, A. E. Cowan, L. J. Taylor-Kearney, H. A. Chang, L. N. Hall, D. Bellieny-Rabelo, H. M. Nisonoff, R. F. Weissman, A. I. Flamholz, D. Ding, , D. F. Savage
The paper maps the sequence-to-function relationship of rubisco by assaying single amino acid mutants in E. coli, identifying conserved positions and mutations that improve CO2 affinity.
bioRxiv · Sep 27, 2023Biochemistry