Soquelitinb, A selective inhibitor of interleukin-2-inducible kinase (ITK), is active in several murine models of T cell-mediated inflammatory disease
L.-Y. Hsu, J. T. Rosenbaum, S. Lindner, Y. Allanore, A. Cauvet, R. D. Pawar, D. Li, M. Van Den Brink, R. A. Miller
This study shows that soquelitinib inhibits ITK and reduces T cell-mediated inflammation in multiple murine models.
bioRxiv · Oct 27, 2023 · PreprintImmunology