G. Chure

Quantifying the varying harvest of fermentation products from the human gut microbiota

The paper quantifies the metabolic flux of fermentation products from the gut microbiota, showing it varies with diet but not microbiota composition.

Anthroponumbers.org: A Quantitative Database Of Human Impacts on Planet Earth

The paper introduces a database of human impacts on Earth, providing curated quantitative data and analysis of their interconnected effects.

An Optimal Regulation of Fluxes Dictates Microbial Growth In and Out of Steady-State

The paper develops a low-dimensional allocation model to predict microbial growth dynamics by optimizing metabolic and translational fluxes using tRNA turnover data from Escherichia coli.

Physiological Adaptability and Parametric Versatility in a Simple Genetic Circuit

This study examines how growth rate and temperature affect gene expression in a genetic circuit, revealing robustness to nutrient changes but temperature-dependent effects not captured by thermodynamic models.

Sequence-Dependent Dynamics of Synthetic and Endogenous RSSs in V(D)J Recombination

The paper quantifies sequence-dependent dynamics of RAG-RSS interactions in V(D)J recombination, revealing how single-bp changes affect PC formation, stability, and cleavage.

The Energetics of Molecular Adaptation in Transcriptional Regulation

The paper links mutations in a transcriptional repressor to biophysical parameters, showing how changes in free energy predict gene expression and epistasis.

Tuning transcriptional regulation through signaling: A predictive theory of allosteric induction

The paper develops a predictive theory of allosteric transcriptional regulation using the Monod-Wyman-Changeux model and validates it with experimental data on bacterial simple repression motifs.