Author

R. Muthuswamy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

K. Odunsi· 2 shared S. Battaglia· 2 shared A. Amobi-McCloud· 1 shared A. Lugade· 1 shared A. Miliotto· 1 shared A. R. McGray· 1 shared B. D. Litchy· 1 shared C. A. Eppolito· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

K. Odunsi

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintFeb 18, 2021

Indoleamine 2,3-dioxygenase upregulates PD-1 expression on ovarian tumor infiltrating CD8+ T cells via kynurenine activation of the aryl hydrocarbon receptor

A. Amobi-McCloud, R. MUTHUSWAMY, S. Battaglia…·K. Odunsi

This study shows that IDO1 promotes PD-1 expression on CD8+ T cells in ovarian tumors through kynurenine-mediated AHR activation, suggesting therapeutic targeting of these pathways.

DOI 10.1101/2021.02.18.431473

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivDec 2, 2020

CXCR6 by increasing retention of memory CD8 T cells in the ovarian tumor microenvironment promotes immunosurveillance and control of ovarian cancer

R. Muthuswamy, A. R. McGray, S. Battaglia…·K. Odunsi

This study identifies CXCR6 as a marker for resident memory CD8 T cells in ovarian cancer, showing its role in enhancing tumor immunosurveillance through increased retention of these cells in the tumor microenvironment.

DOI 10.1136/jitc-2021-003329

humanmouse

𝕏 PostBluesky