Genome-Scale Mutational Signatures Of Aflatoxin In Cells, Mice And Human Tumors
M. N. Huang, W. Yu, W. W. Teoh, M. Ardin, A. Jusakul, A. Ng, A. Boot, B. Abedi-Ardekani, S. Villar, S. S. Myint, R. Othman, S. L. Poon, A. Heguy, M. Olivier, M. Hollstein, , S. Rozen
This study identifies AFB1 mutational signatures across multiple systems and shows their prevalence in HCCs from different regions, highlighting aflatoxin's public health impact.
bioRxiv · Apr 26, 2017Cancer Biology