Pharmacology & ToxicologybioRxivPreprint
JHU-2545 Selectively Shields Salivary Glands and Kidneys during PSMA-Targeted Radiotherapy
M. T. Nedelcovych, R. P. Dash, Y. Wu…·B. S. Slusher
This paper describes the development of JHU-2545, a prodrug that selectively shields salivary glands and kidneys from PSMA-targeted radiotherapy, improving safety without affecting tumor uptake.