Cell BiologybioRxivPreprint
A novel nuclear speckle factor, USP42, promotes homologous recombination repair by resolving DNA double-strand break induced R-loop
M. Matsui, R. Sakasai, M. Abe…·R. Nishi
This study identifies USP42 as a nuclear speckle factor that promotes homologous recombination repair by resolving R-loops and facilitating BRCA1 recruitment to DNA double-strand breaks.
DOI 10.1101/776823