Cell BiologybioRxiv
A novel IKK- and proteasome-independent mechanism of RelA activation triggers senescence associated secretome via transcriptional repression of NFKBIA
M. Kolesnichenko, N. Mikuda, U. E. Höpken…·C. Scheidereit
The paper identifies a novel IKK- and proteasome-independent mechanism of RelA activation in senescent cells that drives the senescence-associated secretome through transcriptional repression of NFKBIA.
DOI 10.15252/embj.2019104296