A small molecule screen identified N-Acetyl-L-cysteine for promoting ex vivo growth of single circulating tumor cells
T. Teng, M. Kamal, O. Iriondo, Y. Amzaleg, C. Luo, A. Thomas, G. Lee, J. D. Nguyen, A. Smith, R. Sposto, M. Yu
The paper identifies N-acetylcysteine (NAC) as a compound that promotes ex vivo growth of single circulating tumor cells by reducing oxidative stress.
bioRxiv · Aug 19, 2020 · PreprintCancer Biology