Author

R. T. Schirra

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Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

B. K. Ganser-Pornillos· 1 shared I. Kucharska· 1 shared K. K. Zadrozny· 1 shared N. F. dos Santos· 1 shared O. Pornillos· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperMicrobiology

B. K. Ganser-Pornillos

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1 paper

Recent·Most cited

MicrobiologybioRxivAug 25, 2022

A molecular switch modulates assembly and host factor binding of the HIV-1 capsid

R. T. Schirra, N. F. dos Santos, K. K. Zadrozny…·O. Pornillos

This study identifies a molecular switch in HIV-1 capsid protein that controls capsid assembly and host factor binding, and is a target for the inhibitor lenacapavir.

DOI 10.1038/s41594-022-00913-5

humanstructural biology

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