SARS-CoV-2 Omicron efficiently infects human airway, but not alveolar epithelium
M. M. Lamers, A. Z. Mykytyn, T. I. Breugem, N. Groen, K. Knoops, D. Schipper, R. van Acker, P. B. van den Doel, T. Bestebroer, C. D. Koopman, C. Reusken, M. J. Muraro, C. H. GeurtsvanKessel, M. E. van Royen, P. J. Peters, , B. L. Haagmans
This study compares the replication efficiency of SARS-CoV-2 Omicron with earlier variants in human airway and alveolar epithelial cells, finding higher replication in airways and reduced replication in alveolar type 2 cells.
bioRxiv · Jan 19, 2022 · PreprintMicrobiology