P. J. Peters

This study investigates the physical association between low density lipoprotein particles and extracellular vesicles using single-particle analysis techniques and shows that LPPs can form complexes with EVs under physiological conditions.

This study compares the replication efficiency of SARS-CoV-2 Omicron with earlier variants in human airway and alveolar epithelial cells, finding higher replication in airways and reduced replication in alveolar type 2 cells.

This study uses airway organoids to investigate M. abscessus infection in CF patients, showing antioxidant pathways can inhibit bacterial growth and enhance antibiotic efficacy.

The paper assesses the replicative fitness of SARS-CoV-2 B.1.1.7 variant in human organoid models and finds higher infectious virus production and fitness compared to an ancestral strain.

This study identifies phospholipid peroxidation as a mechanism enhancing ExoU phospholipase activity, leading to cell necrosis and supporting Pseudomonas aeruginosa pathogenesis.

This study evaluates the Abbott ARCHITECT HIV Ag/Ab Combo Assay's ability to determine recent HIV-1 infection using signal-to-cutoff ratios, finding it suitable for both diagnostic and incidence surveillance.

The paper shows that IL-1R1-dependent signals enhance clearance of cytosolic mycobacteria in vivo, particularly when host immunity is compromised.

The paper shows SARS-CoV-2 infects human gut enterocytes in small intestinal organoids, leading to viral replication and a strong immune response.

This study establishes long-term-expanding human airway organoids from broncho-alveolar biopsies or lavage material, enabling disease modeling of cystic fibrosis, lung cancer, and RSV infection.