Author

N. Groen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:scRNA-seq· 2 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. Z. Mykytyn· 2 shared B. L. Haagmans· 2 shared C. D. Koopman· 2 shared D. Schipper· 2 shared J. Zhang· 2 shared K. Knoops· 2 shared M. J. Muraro· 2 shared M. M. Dickman· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

A. Z. Mykytyn

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A Single-Cell RNA-Seq Analysis Unravels The Heterogeniety Of Primary Cultured Human Corneal Endothelial Cells

P. Catala, N. Groen, V. LaPointe, M. M. Dickman

This study uses single-cell RNA sequencing to analyze primary cultured human corneal endothelial cells, revealing their transcriptomic heterogeneity and suggesting markers for quality assessment.

bioRxiv · Feb 9, 2023 · PreprintCell Biology

SARS-CoV-2 Omicron efficiently infects human airway, but not alveolar epithelium

M. M. Lamers, A. Z. Mykytyn, T. I. Breugem, N. Groen, K. Knoops, D. Schipper, R. van Acker, P. B. van den Doel, T. Bestebroer, C. D. Koopman, C. Reusken, M. J. Muraro, C. H. GeurtsvanKessel, M. E. van Royen, P. J. Peters, , B. L. Haagmans

This study compares the replication efficiency of SARS-CoV-2 Omicron with earlier variants in human airway and alveolar epithelial cells, finding higher replication in airways and reduced replication in alveolar type 2 cells.

bioRxiv · Jan 19, 2022 · PreprintMicrobiology

A single cell transcriptome atlas reveals the heterogeneity of the healthy human cornea and identifies novel markers of the corneal limbus and stroma

P. Catala, N. Groen, J. A. Dehnen, E. Soares, A. J. van Velthoven, R. M. Nuijts, M. M. Dickman, V. L. LaPointe

This study creates a single-cell transcriptome atlas of the healthy human cornea, identifying novel markers for specific cell populations and states.

bioRxiv · Jul 7, 2021 · PreprintCell Biology

Human organoid systems reveal in vitro correlates of fitness for SARS-CoV-2 B.1.1.7

M. M. Lamers, T. I. Breugem, A. Z. Mykytyn, Y. Wang, N. Groen, K. Knoops, D. Schipper, J. van der Vaart, C. D. Koopman, J. Zhang, D. C. Wu, P. B. van den Doel, T. Bestebroer, C. C. GeurtsvanKessel, P. J. Peters, , B. L. Haagmans

The paper assesses the replicative fitness of SARS-CoV-2 B.1.1.7 variant in human organoid models and finds higher infectious virus production and fitness compared to an ancestral strain.

bioRxiv · May 3, 2021 · PreprintMicrobiology