Author

d. pericat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Hessel· 2 shared C. Cougoule· 2 shared E. Meunier· 2 shared K. Santoni· 2 shared M. Pinilla· 2 shared R. Planes· 2 shared A. Henras· 1 shared C. Paget· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersImmunology

A. Hessel

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2 papers

Recent·Most cited

EEF2-inactivating toxins engage the NLRP1 inflammasome and promote epithelial barrier disruption upon Pseudomonas infection

M. Pinilla, R. Mazars, R. Verge, L. Gorse, K. Santoni, K. S. Robinson, G. A. Toh, L. Prouvensier, S. A. Leonicaza, A. Hessel, d. pericat, M. Murris, A. Henras, J. M. Buyck, C. Cougoule, , E. Meunier

This paper shows that Pseudomonas aeruginosa's Exotoxin A activates the NLRP1 inflammasome via EEF2 inactivation, causing epithelial damage and pyroptosis, and identifies ZAK as a key sensor in this process.

bioRxiv · Jan 16, 2023 · PreprintImmunology

Caspase-1-driven neutrophil pyroptosis promotes an incomplete NETosis upon Pseudomonas aeruginosa infection

K. Santoni, D. Pericat, M. Pinilla, S. Bagayoko, A. Hessel, S. A. Leon-Ycaza, E. Bellard, S. Mazeres, E. Doz-Deblauwe, N. Winter, C. Paget, J.-P. Girard, C. Cougoule, R. Poincloux, M. Lamkanfi, , R. Planes

This study shows that Pseudomonas aeruginosa induces Caspase-1-dependent pyroptosis in neutrophils, leading to incomplete NETosis and promoting bacterial spread.

bioRxiv · Jun 28, 2021 · PreprintImmunology