ImmunologybioRxiv
Impaired in vitro Interferon-γ production in patients with visceral leishmaniasis is improved by inhibition of PD1/PDL-1 ligation
Y. Takele, E. Adem, S. U. Franssen…·P. Kropf
This study shows that PD1/PDL-1 inhibition increases IFN-γ production in VL patients, suggesting potential for immune checkpoint therapy.
DOI 10.1371/journal.pntd.0010544