MicrobiologybioRxivPreprint
Genetic screen suggests an alternative mechanism for azide-mediated inhibition of SecA
Rachael Chandler, Mohammed Jamshad, Jack Yule…·Damon Huber
The paper uses a genetic screen to show azide inhibits SecA by causing it to backtrack in its ATPase cycle, disrupting membrane and metal cofactor binding.
DOI 10.1101/173039