Cancer BiologybioRxivPreprint
ENPP1 inhibitor with ultralong drug-target residence time as an innate immune checkpoint blockade cancer therapy
Randolph M. Johnson, Songnan Wang, Jacqueline A. Carozza…·Lingyin Li
A small molecule blocks ENPP1, reviving immune attack on tumors and enhancing immune therapy with minimal side effects in preclinical cancer models.
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