Author

Rayna M. Esch

University of Connecticut

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Pathology· 1

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Approach:experimental assay· 1 Organism:mouse· 1

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David J. GoldhameriD· 1 shared Katherine L. Scalise· 1 shared L. Russell Hanson· 1 shared Liv Nevo· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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David J. GoldhamerORCID

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1 paper

Recent·Most cited

PathologyBonePeer-reviewedFeb 9, 2026

The role of muscle fascia in heterotopic ossification and maintenance of skeletal muscle integrity in fibrodysplasia ossificans progressiva

L. Russell Hanson, Katherine L. Scalise, Rayna M. Esch…·David J. Goldhamer

This study shows that fascial injury, not direct muscle injury, induces heterotopic ossification in FOP by activating Acvr1R206H-expressing fibro-adipogenic progenitors, leading to muscle destruction and impaired regeneration.

DOI 10.1016/j.bone.2026.117829

mouseexperimental assay

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