BiochemistrybioRxivPreprint
FTO separation-of-function mutations alter m6A versus m6Am demethylation selectivity on RNA
Kasun Dilshan Abeyrathne Eluwawalage, Brittany A. Shimanski, Marcin Warmiński…·Jeffrey S. Mugridge
This paper reports engineered FTO mutants that selectively demethylate m6A or m6Am RNA modifications, enabling study of their distinct biological roles.
DOI 10.64898/2026.05.19.726201