Yanbao Yu

This study performs a global proteomic analysis of sea urchin embryos across developmental stages, revealing dynamic protein expression patterns and discordant mRNA-protein correlations.

The paper uses proteomics to identify keratinizing squamous and intestinal metaplasia in urothelium of long-term catheterized SCI patients with chronic UTIs.

The paper characterizes RNA and protein expression in synthetic bacteria Syn1.0 and Syn3A, showing genome minimization alters gene expression and resource allocation.

This paper introduces an in-cell proteomics strategy for plant samples, demonstrating improved speed, simplicity, and proteomic sensitivity compared to conventional methods.

The paper identifies 33 novel phosphoinositide-binding effectors from three intracellular pathogens, revealing conserved α-helical structural motifs distinct from eukaryotic lipid-binding domains.

This study identifies Fibulin-2 as a matrix cue that transduces fibrotic ECM remodeling into mitochondrial metabolic reprogramming in kidney fibrosis.

This study identifies CsdA as the first NAD+ cap reader protein in E. coli, showing it binds NAD+ capped RNA and enhances decapping activity.

This study maps TRMT1's interactome using APEX2-based proximity labeling and DIA mass spectrometry, identifying proteins involved in RNA processing and redox biology.

This paper reports engineered FTO mutants that selectively demethylate m6A or m6Am RNA modifications, enabling study of their distinct biological roles.

This study introduces an in-cell proteomics method to analyze early Xenopus tropicalis embryos, revealing detailed spatiotemporal protein dynamics across cleavage stages.

This study identifies Mfap2 as a key ECM component that regulates kidney repair by linking mechanical cues to metabolic reprogramming through Esr2-mediated transcriptional control.

This study compares transcriptomes of two minimized bacteria to understand gene expression patterns and highlights limitations of bioinformatics alone.

The paper identifies factors influencing RNA sorting into extracellular vesicles, finding size and structuredness significantly affect enrichment of circular and linear RNAs.

This study shows that Chlorobaculum tepidum uses outer membrane vesicles to transport biogenic elemental sulfur, linking OMVs to sulfur metabolism and extracellular sulfur globule formation.

The paper uses whole-cell proteomics to identify novel regulators of ciliogenesis in Xenopus multiciliated cells, revealing 832 upregulated proteins involved in ciliary structures and function.

This paper introduces an in-cell proteomics method for C. elegans that enables high-throughput proteome analysis with minimal sample input and identifies proteomic changes in sod-1 mutants.

This study quantifies how Pseudomonas putida KT2440 couples carbon and energy metabolism during lignin-derived phenolic compound utilization, revealing metabolic remodeling and cofactor production mechanisms.

This paper shows Sideroxydans lithotrophicus ES-1 uses magnetite as a solid electron donor for iron oxidation, with MtoA and cupredoxin proteins involved in this process.

This study shows that inhibiting OGT activates type I interferon-dependent antitumor immunity by enhancing the cGAS-STING pathway through genomic instability.

The study examines microbial dynamics and host interactions in urethral catheter biofilms, showing antibiotic treatments alter composition but fail to eliminate biofilms.

The paper shows that urethral catheters host recurrent polymicrobial biofilms where bacteria exhibit cooperative and competitive interactions.