Molecular BiologyProtein SciencePeer-reviewed
Refined read-out: The hUHRF1 Tandem-Tudor domain prefers binding to histone H3 tails containing K4me1 in the context of H3K9me2/3
Michel Choudalakis, Goran Kungulovski, Rebekka Mauser…·Albert Jeltsch
This study identifies a novel read-out mechanism of UHRF1-TTD binding to H3K4me1-K9me2/3 double marks, showing its role in gene down-regulation and chromatin binding.