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Richard Zhang

Princeton University

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Biology Disciplines

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Developmental Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

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Benjamin J. RaphaeliD· 1 shared Henri SchmidtiD· 1 shared Michelle M. ChaniD· 1 shared William Howard-Snyder· 1 shared

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Benjamin J. RaphaelORCID

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Developmental BiologybioRxivPreprintDec 12, 2025

Inferring Cell Differentiation Dynamics with Unobserved Progenitors

William Howard-Snyder, Richard Zhang, Henri Schmidt…·Benjamin J. Raphael

The paper introduces TROUPE, a framework to infer cell differentiation dynamics from lineage trees, allowing for unobserved progenitor types and providing better rate estimates than existing methods.

3 citations

mousebulk RNA-seq

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