PathologybioRxivPreprint
Changes In LXRα Phosphorylation Promote A Novel Diet-Induced Transcriptome That Alters The Transition From Fatty Liver To Steatohepatitis
Natalia Becares, Matthew C Gage, Lucia Martin-Gutierrez…·Inés Pineda-Torra
This study shows that preventing LXRα phosphorylation at Ser196 reduces hepatic inflammation and fibrosis in mice on a high-fat diet, revealing a novel role for LXR phosphorylation in diet-induced transcriptome changes.
DOI 10.1101/127779