Impact of astrocytic C3-production on neuronal mitochondrial dysfunction in tauopathy mouse models
Chenxu Lei, Bocheng Zhang, Junji Yamaguchi…·Tatsuhiro Hisatsune
This study shows that astrocytic C3 production exacerbates neuronal mitochondrial dysfunction and necroptosis in tauopathy models, and that anserine can mitigate these effects.