Molecular BiologyNucleic Acids ResearchPeer-reviewed
Phosphorylation of HP1/Swi6 relieves competition with Suv39/Clr4 on nucleosomes and enables H3K9 trimethyl spreading.
Dana R Kennedy, Joël P.C. Lemiere, Ahmed A. A. Amine…·Bassem Al‐Sady
This study shows that phosphorylation of HP1/Swi6 reduces competition with Suv39/Clr4 by altering its nucleosome affinity and oligomerization, promoting H3K9me3 spreading in S. pombe.