David O. Morgan

This study identifies intramolecular loops that regulate SARS-CoV-2 N-protein self-association and nucleic acid binding through phosphorylation-dependent conformational changes.

This study determines cryoEM structures of human separase in apo and substrate-bound forms, revealing substrate recognition mechanisms and cleavage regulation.

The paper shows that a phosphate-binding pocket on cyclin B influences CDK substrate phosphorylation and mitotic timing in budding yeast.

This study shows that the truncated N* variant of SARS-CoV-2 nucleocapsid protein can assemble into vRNPs similar to full-length N, requiring the leucine-rich helix and inhibited by a phosphomimetic SR region.