PP2A catalytic subunit alpha is critically required for CD8+ T cell homeostasis and anti-bacterial responses
Xian Zhou, Meilu Li, Minji Ai, Yanfeng Li, Xingxing Zhu, Michael J. Hansen, Jun Zhong, Kenneth L. Johnson, Roman Zenka, Akhilesh Pandey, Larry R. Pease, Hu Zeng
This study shows that PP2A catalytic subunit alpha is essential for CD8+ T cell homeostasis and anti-bacterial responses, with Bcl2 rescue limited to spleen.
bioRxiv · Feb 6, 2024 · PreprintImmunology