Author

Yanfeng Li

Mayo Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Immunology· 3 Cancer Biology· 1 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:mouse· 5 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Hu ZengiD· 3 shared Amy KemperiD· 2 shared Meilu LiiD· 2 shared Michael ChoppiD· 2 shared Weida WangiD· 2 shared Xianshuang LiuiD· 2 shared Xingxing ZhuiD· 2 shared Yi ZhangiD· 2 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersImmunology

Hu ZengORCID

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Peripheral Monocyte-Derived Extracellular Vesicles Establish an Immune-Brain Communication Pathway in Alzheimer's Disease

Mingjin Wang, Weida Wang, Yanfeng Li, Zhongwu Liu, Louie Semaan, Amy Kemper, Xianshuang Liu, Li Zhang, Michael Chopp, Zheng Gang Zhang, Yi Zhang

The paper identifies a peripheral monocyte-derived extracellular vesicle pathway that mediates neuronal injury in Alzheimer's disease and shows IL-1β as a key mediator.

bioRxiv · Aug 27, 2026 · PreprintNeuroscience

ACLY integrates metabolism and chromatin accessibility to enable B Cell activation and humoral immunity

Meilu Li, Zhiqiang Zhang, Xian Zhou, Yanfeng Li, Xingxing Zhu, Aditya Bhagwate, Nagaswaroop Kengunte Nagaraj, Hu Zeng

This study shows ACLY links metabolism to chromatin accessibility in B cells, essential for activation and humoral immunity.

bioRxiv · May 27, 2026 · PreprintImmunology

Engineered Extracellular Vesicles Enriched with the miR-214/199a Cluster Enhance the Efficacy of Chemotherapy for Ovarian Cancer

Weida Wang, Ayesha B. Alvero, Yi Qin, Mingjin Wang, Alexandra Lucienne Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xianshuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang

This paper shows engineered extracellular vesicles carrying miR-214-3p/miR-199a-5p enhance chemotherapy effectiveness in ovarian cancer by reversing chemoresistance and reprogramming tumor EV communication.

Molecular Oncology · Feb 13, 2026Peer-reviewedCancer Biology

Bergeyella cardium variant induces unique cytoplasmic vacuolization cell death

Rudi Mao, Hongwei Pan, Luyu Yang, Zhenyu Fan, Yanfeng Li, Xinran Yu, Zhen Li, Ying Chen, Yang Yu, Wei Wang, Chengjiang Gao, Jun Peng, Tao Xu, Yi Zhang, Xiaopeng Qi

This study identifies Bergeyella cardium variant-induced cytoplasmic vacuolization cell death and shows SLC9A9 and OMVs play key roles in this process.

Cell Discovery · Oct 21, 2025Peer-reviewedCell Biology

Targeting mechanistic target of rapamycin complex 2 attenuates immunopathology in Systemic Lupus Erythematosus

Minji Ai, Xian Zhou, Michele Carrer, Paymaan Jafar‐Nejad, Yanfeng Li, Naomi M. Gades, Mariam P. Alexander, Mario Alejandro Bautista-Vargas, Alí Duarte‐García, Hu Zeng

This study investigates the role of mTORC2 in SLE and shows that targeting mTORC2 reduces immunopathology in both mouse models and human PBMCs.

Rheumatology · Dec 3, 2024Peer-reviewedImmunology

CPT2 mediated fatty acid oxidation is dispensable for humoral immunity

Meilu Li, Xian Zhou, Xingxing Zhu, Yanfeng Li, Taro Hitosugi, Yuzhen Li, Hu Zeng

This study shows that CPT2-mediated fatty acid oxidation is not essential for humoral immunity in mice, as CPT2 deficiency does not impair B cell development, activation, or antibody production.

The Journal of Immunology · Sep 11, 2024Peer-reviewedImmunology