Cell BiologybioRxivPreprint
RIPK3-dependent sequential recruitment of MLKL and RIPK1 drives PANoptotic cell death and chemokine production
Yu Yang, Yue Wang, Yang Wang…·Hua Zhong
This study identifies a RIPK3-dependent PANoptosome assembly mechanism that integrates pyroptotic, apoptotic, and necroptotic pathways, driving immunogenic cell death and chemokine production.