BiochemistryJournal of Biological ChemistryPeer-reviewed
Cryo-EM Structures Reveal Upstream DNA Interactions within the Mitochondrial Transcription Initiation Complex
Rory E. Sharkey, Caitlin Schroeder, Xiangyu Deng…·Yang Gao
The paper presents cryo-EM structures of mitochondrial transcription initiation complexes, showing how TFAM and PolRMT interact with upstream DNA to regulate transcription initiation and specificity.
DOI 10.1016/j.jbc.2026.113611