Author

Ruili Cao

Institute for Protein Innovation

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:protein sequence· 2 Research Focus:software / tool· 2 Research Focus:database / resource· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Andre A. R. TeixeiraiD· 2 shared Deepash KothiwaliD· 2 shared Haisun ZhuiD· 2 shared Alina Airich· 1 shared Allan A. MillsiD· 1 shared David SprinzakiD· 1 shared Haixia ZhouiD· 1 shared Hanjie JiangiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBioinformatics

Andre A. R. TeixeiraORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BioinformaticsNucleic Acids ResearchPeer-reviewedOct 29, 2026

✦ In-depth digest

OpenAntigens: a structure-aware database for antigen construct design across the human cell-surface and secreted proteome

Andre A. R. Teixeira, Haisun Zhu, Deepash Kothiwal…·Allan A. Mills

A static web database proposes 55 305 construct suggestions for 5328 human secreted and cell-surface proteins, using AlphaFold pLDDT and PAE, with ortholog, paralog and BLAST cross-reactivity context.

DOI 10.1093/nar/gkag1051

humanmouse

𝕏 PostBluesky

BioinformaticsbioRxivPreprintSep 24, 2026

An interpretable open platform for sequence-based antibody developability prediction

Hoan N. Nguyen, Deepash Kothiwal, Yang Su…·Andre A. R. Teixeira

DELPHI is an open platform for predicting antibody developability from sequence, achieving high AUC scores and enabling residue-level engineering insights.

DOI 10.64898/2026.09.16.750421

protein sequencemachine learning (classical)

𝕏 PostBluesky

BiochemistryStructurePeer-reviewedAug 8, 2024

Structural Requirements for Activity of Mind bomb1 in Notch Signaling

Ruili Cao, Oren Gozlan, Alina Airich…·Stephen C. Blacklow

This study identifies the structural requirements of MIB1 for ubiquitin transfer in Notch signaling, showing that RING3 is essential for catalytic activity and dimerization.

7 citations

experimental assayprotein folding & dynamics

𝕏 PostBluesky