MicrobiologyCellPeer-reviewed
Identification and targeting of microbial putrescine acetylation in bloodstream infections
Jared R. Mayers, Jack Varon, Ruixuan Zhou…·Emily P. Balskus
The paper identifies bacterially-derived N-acetylputrescine as a marker of severe gram-negative bloodstream infections and shows that inhibiting its synthesis reduces bacterial growth and antibiotic resistance.