MicrobiologybioRxivPreprint
The oral pathogen Porphyromonas gingivalis resists the antimicrobial peptide LGL13K and evades the D-enantiomer by synonymous mutations in hagA
Sven-Ulrik Gorr, Ruoqiong Chen, Juan E. Abrahante, Paul B.M. Joyce
This study identifies synonymous mutations in hagA that confer resistance to DGL13K in P. gingivalis by altering mRNA structure and reducing HagA expression, without affecting mRNA levels.