ImmunologybioRxivPreprint
SB 11285, a Novel Canonical Purine-Pyrimidine Cyclic Dinucleotide, is a Systemically Bioavailable STING Agonist for Cancer Immunotherapy
Rupa Challa, Shenghua Zhou, Anjaneyulu Sheri…·Radhakrishnan P. Iyer
This paper describes the development of SB 11285, a potent and bioavailable STING agonist showing antitumor activity in mouse models and undergoing clinical trials for cancer immunotherapy.
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