Author

S. A. Chitre

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Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

H. Xu· 1 shared I. A. Akinyemi· 1 shared J. A. Lednicky· 1 shared J. C. Loeb· 1 shared M. T. McIntosh· 1 shared S. Bhaduri-McIntosh· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMicrobiology

H. Xu

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1 paper

Recent·Most cited

MicrobiologybioRxivPreprintOct 27, 2020

SARS-CoV-2 viroporin triggers the NLRP3 inflammatory pathway

H. Xu, S. A. Chitre, I. A. Akinyemi…·S. Bhaduri-McIntosh

This paper identifies ORF3a as a SARS-CoV-2 viroporin that activates the NLRP3 inflammasome by causing potassium efflux, leading to IL-1β expression and inflammation.

DOI 10.1101/2020.10.27.357731

humanproteomics

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