BiophysicsbioRxivPreprint
Structural basis of interdomain communication in PPARγ
S. A. Mosure, P. Munoz-Tello, K.-T. Kuo…·D. Kojetin
This study identifies a conserved Trp-Pro motif in PPARγ AF-1 that undergoes cis/trans isomerization, enabling interdomain communication with the LBD and affecting transcriptional activity.
DOI 10.1101/2022.07.13.499031