Author

S. A. Shaffer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Becerra-Artiles· 1 shared A. Zaveri· 1 shared C. J. Reames· 1 shared C. M. Sassetti· 1 shared C. Trujillo· 1 shared D. Schnappinger· 1 shared D. T. Hung· 1 shared E. Rubin· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. Becerra-Artiles

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Immunopeptidome profiling of human coronavirus OC43-infected cells identifies CD4 T cell epitopes specific to seasonal coronaviruses or cross-reactive with SARS-CoV-2

A. Becerra-Artiles, P. P. Nanaware, K. Muneeruddin, G. C. Weaver, S. A. Shaffer, J. M. Calvo-Calle, L. J. Stern

This study identifies CD4 T cell epitopes from OC43-infected cells, revealing both OC43-specific and cross-reactive epitopes with SARS-CoV-2.

bioRxiv · Dec 1, 2022 · PreprintImmunology

Compartmentalized Cell Envelope Biosynthesis in Mycobacterium tuberculosis

J. Puffal, I. L. Sparks, J. R. Brenner, X. Li, J. D. Leszyk, J. Hayashi, S. A. Shaffer, Y. S. Morita

This paper identifies the conserved intracellular membrane domain (IMD) in Mycobacterium tuberculosis, showing it is a specialized compartment for synthesizing virulence-related lipids.

bioRxiv · Jan 7, 2022Microbiology

Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy

E.-I. Koh, P. O. Oluoch, N. Ruecker, M. K. Proulx, V. Soni, K. C. Murphy, K. G. Papavinasasundaram, C. J. Reames, C. Trujillo, A. Zaveri, M. D. Zimmerman, R. Aslebagh, R. E. Baker, S. A. Shaffer, K. M. Guinn, , C. M. Sassetti

This study maps chemical-genetic interactions in Mycobacterium tuberculosis to identify how carbon metabolism and cell wall structure affect drug efficacy, revealing environment-dependent and -independent interactions.

bioRxiv · Apr 8, 2021Microbiology