Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
N. D. Walter, J. P. Ernest, C. Dide-Agossou…·G. T. Robertson
The paper shows that Mycobacterium tuberculosis in different lung microenvironments have distinct phenotypes and treatment responses in a mouse model.
E. Nuermberger, R. Tasneen, A. Garcia…·K. E. Dooley
This paper tests novel tuberculosis treatment regimens in mice, finding that BZM-based regimens show improved sterilizing activity compared to standard care.
S. Li, N. C. Poulton, J. S. Chang…·J. M. Rock
This study uses a CRISPR interference platform to map drug resistance pathways in Mtb, identifying new intrinsic and acquired resistance mechanisms and potential drug targets.
E.-I. Koh, P. O. Oluoch, N. Ruecker…·C. M. Sassetti
This study maps chemical-genetic interactions in Mycobacterium tuberculosis to identify how carbon metabolism and cell wall structure affect drug efficacy, revealing environment-dependent and -independent interactions.
C. G. M. Winchell, B. B. Mishra, J. Y. Phuah…·J. L. Flynn
This study evaluates IL-1 blockade as an adjunct to linezolid therapy for tuberculosis in mice and macaques, finding reduced inflammation and preserved host response without impairing treatment efficacy.