Author

C. Trujillo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1

Frequent Co-Authors

S. Ehrt· 3 shared T. R. Ioerger· 3 shared C. M. Sassetti· 2 shared D. Schnappinger· 2 shared K. C. Murphy· 2 shared K. G. Papavinasasundaram· 2 shared K. M. Guinn· 2 shared M. Fitzgerald· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

S. Ehrt

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy

E.-I. Koh, P. O. Oluoch, N. Ruecker, M. K. Proulx, V. Soni, K. C. Murphy, K. G. Papavinasasundaram, C. J. Reames, C. Trujillo, A. Zaveri, M. D. Zimmerman, R. Aslebagh, R. E. Baker, S. A. Shaffer, K. M. Guinn, , C. M. Sassetti

This study maps chemical-genetic interactions in Mycobacterium tuberculosis to identify how carbon metabolism and cell wall structure affect drug efficacy, revealing environment-dependent and -independent interactions.

bioRxiv · Apr 8, 2021Microbiology

Genetic models of latent tuberculosis in mice reveal differential control by adaptive immunity

H. Su, K. Lin, D. Tiwari, C. Healy, C. Trujillo, Y. Liu, T. R. Ioerger, D. Schnappinger, S. Ehrt

This study develops genetic mouse models of latent tuberculosis, revealing that adaptive immunity differentially controls relapse depending on the model used.

bioRxiv · Feb 8, 2021Microbiology

E2F4 as a single multifactorial target against Alzheimer's disease

N. Lopez-Sanchez, M. Ramon-Landreau, C. Trujillo, A. Garrido-Garcia, J. M. Frade

This study shows that inhibiting E2F4 in Alzheimer's mice reduces inflammation, Aβ proteostasis issues, and cognitive decline, suggesting E2F4 as a therapeutic target.

bioRxiv · May 8, 2020 · PreprintPathology

Large-scale chemical-genetics yields new Mycobacterium tuberculosis inhibitor classes

E. O. Johnson, E. LaVerriere, M. Stanley, E. Office, E. Meyer, T. Kawate, J. Gomez, R. E. Audette, N. Bandyopadhyay, N. Betancourt, K. Delano, I. Da Silva, J. Davis, C. Gallo, M. Gardner, , Schnappinge

This study uses a novel chemical-genetics screening strategy to identify new inhibitors of Mycobacterium tuberculosis, revealing novel compound classes targeting previously unexplored bacterial targets.

bioRxiv · Jan 16, 2019Microbiology