ImmunologybioRxivPreprint
E3 Ligase UBR5 HECT domain mutations in lymphoma control maturation of B cells via alternative splicing
S. A. Swenson, T. J. Gilbreath, H. Vahle…·S. M. Buckley
This study shows that UBR5 HECT domain mutations in lymphoma disrupt B cell maturation by altering alternative splicing, suggesting a role in mantle cell lymphoma initiation.
DOI 10.1101/732180