Reprogramming Human Inflammatory Macrophages in Symptomatic Carotid Stenosis: Potential Mechanisms for Stabilisation of Atherosclerotic Carotid Plaques
K. Kocsy, S. Deshmukh, S. Nawaz, A. N. Ali, S. Baig, J. S. Balami, A. Majid, E. Kiss-Toth, S. Francis, J. Redgrave
This study examines macrophage phenotypes in carotid plaques and shows glucocorticoids can reprogram macrophages to reduce inflammation and lipid uptake, potentially stabilizing atherosclerotic plaques.
bioRxiv · Jun 11, 2024 · PreprintCell Biology