Cancer BiologybioRxivPreprint
Pyruvate dehydrogenase kinase expression profile is a biomarker for cancer sensitivity to dichloroacetate-mediated growth inhibition.
B. P. Gang, M. Rooke, R. C. Sun…·A. C. Blackburn
This study identifies PDK expression profiles as a biomarker for cancer sensitivity to DCA, showing that low PDK3 expression correlates with higher DCA sensitivity.
DOI 10.1101/2023.09.18.557101