PathologybioRxivPreprint
Human hepatocyte PNPLA3 148M exacerbates rapid non-alcoholic steatohepatitis development in chimeric mice
M. Kabbani, E. Michailidis, S. Steensels…·Y. P. de Jong
This study shows that the PNPLA3 148M variant in human hepatocytes worsens non-alcoholic steatohepatitis in chimeric mice on a hypercaloric diet.