S. Boyce

Identification and characterization of the T cell receptor (TCR) repertoire of the Cynomolgus macaque (Macaca Fascicularis)

The paper characterizes the T cell receptor repertoire in Cynomolgus macaques using single-cell RNA sequencing and identifies similarities with human and Rhesus macaque TCR repertoires.

CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection

This study shows CD4 T cell help enhances CD8 T cell function and prevents exhaustion during M. tuberculosis infection, suggesting vaccines targeting both cell types may be more effective.

Limited recognition of Mycobacterium tuberculosis-infected macrophages by polyclonal CD4 and CD8 T cells from the lungs of infected mice

The paper assesses T cell recognition of Mtb-infected macrophages in mice and finds that CD4 T cells more effectively recognize these cells than CD8 T cells, with BCG vaccination eliciting such responses.